TINA in Triplex Forming Probes

Increased Tm and ΔTm by TINA in DNA Probes can Potentially Increase Sensitivity and Specificity of DNA Hybridization Assays

U. V. Schneider1, N. D. Mikkelsen1, N. Jøhnk1, J. K. Severinsen1, L. M. Okkels1, T. Klinge1, E. B. Pedersen2, H. Westh1, G. Lisby1; 1QuantiBact Inc, Hvidovre, DENMARK 2Dept. of Chemistry, Univ. of Southern Denmark, Odense, DENMARK