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Twisted Intercalating Nucleic Acid - TINA

Twisted Intercalating Nucleic Acid - TINA

Twisted Intercalating Nucleic Acid - TINA is an intercalator currently available in two variants.

ortho-TINA designed to stabilize Watson-Crick based antiparallel DNA duplex helixes (as seen in the left picture) and para-TINA designed to stabilize Hoogsteen type triplex helixes and quadruplex helixes (as seen in the right picture)

 

 

 

 

 

 

 

 

 

 

 

 

 

Note: Stuctures were made in YASARA